AUSTEDO XR should be taken:
Once daily
With water
Whole (do not
crush or break)
With or without food
Once-daily AUSTEDO XR (deutetrabenazine) extended-release tablets is a titrated medication, which means your doctor will adjust your dose up or down until you find the dose that provides effective movement reduction while ensuring the medicine is tolerated.
Available as a sample or with a prescription from your doctor
Sample Titration Kit
Given to you at your doctor’s office.
or
Prescription Titration Kit
Prescription given to you to be filled at your pharmacy. Participating pharmacies will apply a 30-day Free Trial Voucher* to your prescription so it is no cost to you.
*The 30-Day Free Trial Voucher is only for new patients. Voucher is good for up to 4 weeks of titration or 30 days of medication.
Packaging not to scale.
This is the dosing schedule for the Titration Kit. Upon completion of the kit, your doctor will write you a prescription for AUSTEDO XR and determine what daily dose is right for you.
Titration Schedule
Once-daily Dosing (mg)
Dosing Totals
Week 1
12 mg
Week 2
18 mg
Week 3
24 mg
Week 4
30 mg
Titration
Schedule
Once-daily
Dosing (mg)
Dosing
Totals
Week 1
12 mg
Week 2
18 mg
Week 3
24 mg
Week 4
30 mg
AUSTEDO XR is available in 6 mg, 12 mg, and 24 mg extended-release tablets and can be combined up to a daily maximum strength of 48 mg. In one clinical study, the average dose of AUSTEDO® (deutetrabenazine) tablets after treatment was ~38 mg daily.*
*Once-daily AUSTEDO XR contains the same active ingredient as twice-daily AUSTEDO. Data on this page is based on twice-daily dosing.1 Pills are for illustration only and not actual size or likeness.
Reaching your maintenance dose1
Once you reach a dose that provides effective movement reduction and is tolerated, that will become your maintenance dose—the dose you stay on moving forward.
It’s important to take AUSTEDO XR exactly as prescribed by your doctor. If you experience a change in symptoms, share these details with your doctor as they made decide to adjust your dose.
Once daily
With water
Whole (do not
crush or break)
With or without food
Twice daily
With water
Whole (do not
crush or break)
With food
If you cannot swallow AUSTEDO XR/AUSTEDO tablets whole, tell your healthcare provider. You may need a different medication.
Use these tips to help ensure you take AUSTEDO XR as prescribed:
For additional information about how to take AUSTEDO XR, please read the Medication Guide. Ask your doctor if you have any questions about taking AUSTEDO XR.
Download the HD Chorea Treatment Tracking Guide to record
when AUSTEDO XR is taken and note any questions for your doctor.
The information on this site is intended for healthcare professionals in the United States. Are you a healthcare professional in the United States?
References:
1. AUSTEDO® XR (deutetrabenazine) extended-release tablets/AUSTEDO® tablets current Prescribing Information. Parsippany, NJ: Teva Neuroscience, Inc.